系统性红斑狼疮(SLE)是一种自身免疫疾病，以产生多种自身抗体、以产生多种自身抗体、免疫系统异常激活为特点，累及全身多个组织器官。可以造成患者的多个器官受损，临床表现多样，严重者危及生命，致死率在自身免疫病中居高不下。世界范围内，亚洲人SLE的发病率较高，其中女性患者占90%，尤其是生育期女性，严重影响生育能力。我国狼疮的患病率为1‰，是西方白种人群的8-10倍，发病人群高达数百万，是名副其实的“狼疮王国”。与欧美人群相比，中国人群SLE发病率更高，发病年龄更早，病情更为严重。
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